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Experience with the combination of dutasteride and tamsulosin in the long-term management of benign prostatic hyperplasia.
MedLine Citation:
PMID:  23024707     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) commonly affect older men. These bothersome symptoms can lead to a decreased quality of life. Currently, two classes of drugs - α-adrenergic blockers and 5α-reductase inhibitors - are prescribed to treat LUTS secondary to BPH. Due to their different mechanisms of action, these medications work in a synergistic manner. Trials of combination therapy have been conducted to assess its effect compared with monotherapy. Current data support combination therapy in men with moderately enlarged prostates and moderate to severe symptoms.
Authors:
Bilal Chughtai; Dean S Elterman; Richard Lee; Alexis E Te; Steven A Kaplan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Therapeutic advances in urology     Volume:  4     ISSN:  1756-2880     ISO Abbreviation:  Ther Adv Urol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101487328     Medline TA:  Ther Adv Urol     Country:  England    
Other Details:
Languages:  eng     Pagination:  267-72     Citation Subset:  -    
Affiliation:
James Buchanan Brady Department of Urology, Weill Cornell Medical College of Cornell University, New York, USA.
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