Document Detail

Experience with an albumin-glutaraldehyde tissue adhesive in sealing air leaks after bullectomy.
MedLine Citation:
PMID:  14721826     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The purpose of this study was to evaluate the effectiveness of an albumin-glutaraldehyde tissue adhesive (BioGlue Surgical Adhesive) in preventing air leaks after bullectomy. METHODS: Between January 1999 and June 2002, BioGlue was applied over the staple or suture lines of 21 consecutive patients who underwent resection of bullae for persistent or recurrent pneumothorax. An age- and sex-matched control group of 19 bullectomy patients from our center was used for comparison. RESULTS: Air leak duration was significantly reduced in the BioGlue group (mean, 0.42 days; range, 0-2 days), compared with the control group (mean, 3.68 days; range, 2-11 days; P < .001). Chest tube drainage time was reduced to a mean of 2.33 days (range, 2-4 days) in the BioGlue group, compared with a mean of 5.42 days (range, 3-12 days) in the control group (P < .05). Morbidity and hospital stay length were slightly lower in the BioGlue group. There was no mortality or BioGlue-related complication in this patient cohort. CONCLUSIONS: The use of BioGlue as a surgical lung sealant significantly decreased the duration of postoperative air leaks and the time to chest tube removal. Use of BioGlue facilitates the postoperative course following bullectomy.
Konstantinos Potaris; Peter Mihos; Ioannis Gakidis
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  The heart surgery forum     Volume:  6     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2003  
Date Detail:
Created Date:  2004-01-14     Completed Date:  2004-05-04     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  429-33     Citation Subset:  IM    
Department of Thoracic Surgery, General Hospital of Attica KAT, Kifissia, Greece.
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MeSH Terms
Albumins / therapeutic use
Case-Control Studies
Chest Tubes
Chi-Square Distribution
Glutaral / therapeutic use
Length of Stay
Middle Aged
Pneumothorax / surgery*
Postoperative Complications / therapy*
Proteins / therapeutic use*
Retrospective Studies
Tissue Adhesives / therapeutic use*
Reg. No./Substance:
0/Albumins; 0/Bio-glue; 0/Proteins; 0/Tissue Adhesives; 111-30-8/Glutaral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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