Document Detail

Experience with the EndoPap device for the cytologic detection of uterine cancer and its precursors: a comparison of the EndoPap with fractional curettage or hysterectomy.
MedLine Citation:
PMID:  2403131     Owner:  NLM     Status:  MEDLINE    
Cytologic assessment of the endometrium with the EndoPap sampler was compared with curettage or hysterectomy in 249 women with symptoms. The sensitivities for the detection of primary corpus cancer and hyperplasia were 0.90 (59/66) and 0.58 (18/31), respectively. All six cases of atypical endometrial hyperplasia were detected by the EndoPap device. Malignant EndoPap cytologic findings were present in 4 of 10 patients with a primary adnexal malignancy and normal endometrial histologic findings. Ninety-two percent of primary uterine cervical cancers were detected by EndoPap cytologic sampling. The specificity for the cytologic diagnosis of benign conditions was 0.93. EndoPap cytologic sampling has a reasonably high sensitivity for the detection of uterine cancers and preinvasive endometrial lesions with a high risk of progression to carcinoma. Further evaluation as to its usefulness in a screening program for uterine and adnexal cancers in postmenopausal women should be considered.
J P LaPolla; S Nicosia; C McCurdy; C Songster; E Ruffolo; W S Roberts; M S Hoffman; J V Fiorica; D Cavanagh
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  163     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-10-24     Completed Date:  1990-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1055-9; discussion 1059-60     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of South Florida, Tampa.
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MeSH Terms
Cervix Uteri / pathology*
Dilatation and Curettage
Endometrial Hyperplasia / pathology
Precancerous Conditions / diagnosis*
Uterine Neoplasms / diagnosis*,  pathology,  surgery
Vaginal Smears* / instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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