| Experience with the EndoPap device for the cytologic detection of uterine cancer and its precursors: a comparison of the EndoPap with fractional curettage or hysterectomy. | |
| | |
MedLine Citation:
|
PMID: 2403131 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cytologic assessment of the endometrium with the EndoPap sampler was compared with curettage or hysterectomy in 249 women with symptoms. The sensitivities for the detection of primary corpus cancer and hyperplasia were 0.90 (59/66) and 0.58 (18/31), respectively. All six cases of atypical endometrial hyperplasia were detected by the EndoPap device. Malignant EndoPap cytologic findings were present in 4 of 10 patients with a primary adnexal malignancy and normal endometrial histologic findings. Ninety-two percent of primary uterine cervical cancers were detected by EndoPap cytologic sampling. The specificity for the cytologic diagnosis of benign conditions was 0.93. EndoPap cytologic sampling has a reasonably high sensitivity for the detection of uterine cancers and preinvasive endometrial lesions with a high risk of progression to carcinoma. Further evaluation as to its usefulness in a screening program for uterine and adnexal cancers in postmenopausal women should be considered. |
| | |
Authors:
|
J P LaPolla; S Nicosia; C McCurdy; C Songster; E Ruffolo; W S Roberts; M S Hoffman; J V Fiorica; D Cavanagh |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 163 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1990 Sep |
Date Detail:
|
Created Date: 1990-10-24 Completed Date: 1990-10-24 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1055-9; discussion 1059-60 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, University of South Florida, Tampa. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cervix Uteri / pathology* Dilatation and Curettage Endometrial Hyperplasia / pathology Female Humans Hysterectomy Precancerous Conditions / diagnosis* Uterine Neoplasms / diagnosis*, pathology, surgery Vaginal Smears* / instrumentation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Eclampsia. VI. Maternal-perinatal outcome in 254 consecutive cases.
Next Document: Outpatient obstetric management of women with type I diabetes.