Document Detail

Experience of using heat citric acid disinfection method in central dialysis fluid delivery system.
MedLine Citation:
PMID:  20514548     Owner:  NLM     Status:  MEDLINE    
We applied the heat citric acid disinfection method in the main part of the central dialysis fluid delivery system (MPCDDS), which consists of a multiple-patient dialysis fluid supply unit, dialysis console units, and dialysis fluid piping. This disinfection method has been used for single-patient dialysis machines, but this is the first trial in the MPCDDS. We examined, by points of safety and disinfection effect, whether this disinfection method is comparable to conventional disinfection methods in Japan. The conventional disinfection method is a combination of two disinfectants, sodium hypochlorite and acetic acid, used separately for protein removal and decalcification. Consequently, total microbial counts and endotoxin concentrations fully satisfied the microbiological requirements for standard dialysis fluid of ISO 11663. From our results and discussion, this heat citric acid disinfection method is proved to be safe and reliable for MPCDDS. However, to satisfy the microbiological requirements for ultrapure dialysis fluid, further consideration for this method in MPCDDS including the reverse osmosis device composition and piping is necessary.
Koji Sakuma; Nobuko Uchiumi; Sumihiko Sato; Nobuhiko Aida; Taketo Ishimatsu; Tadaaki Igoshi; Yoshihiro Kodama; Hiroyuki Hotta
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Publication Detail:
Type:  Journal Article     Date:  2010-06-01
Journal Detail:
Title:  Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs     Volume:  13     ISSN:  1619-0904     ISO Abbreviation:  J Artif Organs     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-21     Completed Date:  2011-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815648     Medline TA:  J Artif Organs     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  145-50     Citation Subset:  IM    
Sato Clinic Hemodialysis Center, 2138-4 Wakamatsu-cho, Wakaba-ku, Chiba, 264-0021, Japan.
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MeSH Terms
Citric Acid*
Disinfection / methods*
Hot Temperature*
Renal Dialysis*
Reg. No./Substance:
0/Disinfectants; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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