Document Detail


Expectations and limitations of endomyocardial biopsy.
MedLine Citation:
PMID:  3915878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endomyocardial biopsy represents an attempt at applying tissue examination to the diagnosis of primary myocardial disease. The right ventricular septum is biopsied from either the internal jugular or femoral venous approach. Left ventricular endomyocardial biopsy has not gained widespread acceptance in North America. A complication rate of 1-4% has been reported. Clinical indications for endomyocardial biopsy include acute cardiac allograft rejection, adriamycin cardiotoxicity and the differentiation of restrictive myopathy from constrictive pericardial disease. The biopsy of patients with idiopathic dilated congestive myopathy to find a treatable form of myocarditis remains controversial and principally a research tool. Only 5-25% of patients with dilated cardiomyopathy are found to have myocarditis and immunosuppressive therapy in these patients has yet to be proven beneficial.
Authors:
A S Mills; A Hastillo; J A Thompson; M L Hess
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  1     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:    1985 Nov-Dec
Date Detail:
Created Date:  1986-11-07     Completed Date:  1986-11-07     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  358-62     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Biopsy / adverse effects,  methods
Cardiomyopathies / chemically induced,  pathology*
Doxorubicin / adverse effects
Graft Rejection
Heart Transplantation
Humans
Myocardium / pathology*
Grant Support
ID/Acronym/Agency:
RR 00065/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
23214-92-8/Doxorubicin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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