Document Detail


Expectant management of suspected ectopic pregnancies even with rising beta-subunit human chorionic gonadotropin levels. A clinical prospective study.
MedLine Citation:
PMID:  7526807     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective study was undertaken to evaluate possibility of expectant management of ectopic pregnancy in a selected group of patients with few symptoms, no gestational sac on sonography, and rising but low beta hCG levels. Using the above mentioned criteria, 26 patients were enrolled during prospective study period of 24 month. Five patients (19.2%) had a ruptured tubal pregnancy during the period of observation. Ten patients (38.5%) underwent laparoscopy with subsequent surgery for tubal pregnancy. The indication for laparoscopy in all 10 cases was abdominal pain. In all these 10 patients the pregnancy was unruptured. The remaining 11 patients (42.3%) escaped surgical intervention. Three had intrauterine pregnancies. In the remaining 8 patients the diagnosis remained presumed ectopic. The mean interval from admission of beta hCG level of < 5 mIU/ml in these 8 patients was 19.2 +/- 8.4 days. They were inpatients until the beta hCG level begun to decline. Thereafter, the patients were observed as outpatients. We conclude that in carefully selected cases of suspected ectopic pregnancies with rising but low beta hCG levels, expectant management is appropriate as long as the patient remains relatively asymptomatic.
Authors:
S Lurie; Z Katz; R Goldshmit; Z Gotlibe; V Insler
Related Documents :
8062937 - Relative operating characteristic analysis in reproductive medicine: comparison of prog...
17545687 - Highly specific and sensitive rise in days 14-17 pro-alphac inhibin with clinical pregn...
8559527 - Elevated second-trimester maternal serum hcg alone or in combination with elevated alph...
12169437 - Metabolism of recombinant progastrin in sheep.
1430487 - A method for combining united states and canadian bull evaluations.
7254057 - "prolonged pregnancy" after oral contraceptive therapy.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  255     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  1994  
Date Detail:
Created Date:  1994-12-20     Completed Date:  1994-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Algorithms
Chorionic Gonadotropin / blood*
Chorionic Gonadotropin, beta Subunit, Human
Diagnosis, Differential
Female
Humans
Immunoradiometric Assay
Infant, Newborn
Laparoscopy
Monitoring, Physiologic
Peptide Fragments / blood*
Predictive Value of Tests
Pregnancy
Pregnancy, Tubal / diagnosis*,  surgery
Prospective Studies
Rupture, Spontaneous
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Substance P and calcitonin gene-related peptide modulate leukocyte infiltration to mouse skin during...
Next Document:  Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding.