| Expectant management of first-trimester spontaneous abortion. | |
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MedLine Citation:
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PMID: 7815886 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Approximately 15% of registered pregnancies end in spontaneous abortion, and for 50 years or so dilatation and curettage (D&C) has been the usual management. In a prospective randomised trial we compared the clinical results after either expectant management or D&C, for miscarriages of less than 13 weeks' gestation in which transvaginal ultrasound examination showed intrauterine tissue and/or blood clots with a diameter 15-50 mm. 103 patients were randomised to expectant management and spontaneous resolution of pregnancy occurred within 3 days in 81 cases (79%). 52 patients were randomised to D&C. 3 infections were diagnosed among patients who underwent expectant management (3%); 5 infections and 1 case of postoperative anaemia were observed among patients randomised to D&C (11%). The duration of vaginal bleeding was a mean of 1.3 days longer in the expectant management group (p < 0.02). Convalescence time, time during which patients experienced pain, and packed-cell volume 3 and 14 days after inclusion did not differ significantly between the groups. This study shows that expectant management of selected cases of spontaneous abortion has a similar outcome to D&C. |
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Authors:
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S Nielsen; M Hahlin |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lancet Volume: 345 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-02-07 Completed Date: 1995-02-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 84-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital, University of Gothenburg, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
/
complications,
therapy*,
ultrasonography Convalescence Dilatation and Curettage / adverse effects Female Humans Pregnancy Pregnancy Trimester, First Prospective Studies Ultrasonography, Prenatal |
| Comments/Corrections | |
Comment In:
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Lancet. 1995 Feb 11;345(8946):387
[PMID:
7845134
]
Lancet. 1995 May 6;345(8958):1179-80 [PMID: 7794365 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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