Document Detail

Expectant management of first-trimester spontaneous abortion.
MedLine Citation:
PMID:  7815886     Owner:  NLM     Status:  MEDLINE    
Approximately 15% of registered pregnancies end in spontaneous abortion, and for 50 years or so dilatation and curettage (D&C) has been the usual management. In a prospective randomised trial we compared the clinical results after either expectant management or D&C, for miscarriages of less than 13 weeks' gestation in which transvaginal ultrasound examination showed intrauterine tissue and/or blood clots with a diameter 15-50 mm. 103 patients were randomised to expectant management and spontaneous resolution of pregnancy occurred within 3 days in 81 cases (79%). 52 patients were randomised to D&C. 3 infections were diagnosed among patients who underwent expectant management (3%); 5 infections and 1 case of postoperative anaemia were observed among patients randomised to D&C (11%). The duration of vaginal bleeding was a mean of 1.3 days longer in the expectant management group (p < 0.02). Convalescence time, time during which patients experienced pain, and packed-cell volume 3 and 14 days after inclusion did not differ significantly between the groups. This study shows that expectant management of selected cases of spontaneous abortion has a similar outcome to D&C.
S Nielsen; M Hahlin
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lancet     Volume:  345     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-02-07     Completed Date:  1995-02-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  84-6     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital, University of Gothenburg, Sweden.
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MeSH Terms
Abortion, Spontaneous / complications,  therapy*,  ultrasonography
Dilatation and Curettage / adverse effects
Pregnancy Trimester, First
Prospective Studies
Ultrasonography, Prenatal
Comment In:
Lancet. 1995 Feb 11;345(8946):387   [PMID:  7845134 ]
Lancet. 1995 May 6;345(8958):1179-80   [PMID:  7794365 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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