Document Detail

Expansion pattern of terminal air-spaces in the premature rabbit lung after tracheal deposition of surfactant.
MedLine Citation:
PMID:  576337     Owner:  NLM     Status:  MEDLINE    
The expansion pattern of the lungs of full-term and premature newborn rabbits was evaluated by direct observation of the lung surface during an inflation-deflation cycle, with particular reference to the effect of tracheal deposition of surfactant before the first breath. In non-treated premature fetuses, aeration of alveoli was initiated at an endotracheal pressure of 35 cm H2O; the mean corresponding 'opening pressure' was 25 cm H2O in both full-term and surfactant-treated premature animals. The process of alveolar aeration was asynchronous in all groups but at maximal inflation pressure (35 cm H2O) the expansion pattern was uniform in full-term and surfactant-treated premature fetuses; these animals also developed residual volume. In non-treated premature animals aeration was patchy, even at maximal inflation, and the lungs emptied at the end of deflation.
G Grossmann
Related Documents :
8713657 - Rapid tracheal infusion of surfactant versus bolus instillation in rabbits: effects on ...
2612447 - Effect of lung collapse on alveolar surfactant in rabbits subjected to unilateral pneum...
6566397 - Lung expansion in premature newborn rabbits treated with emulsified synthetic surfactan...
12015377 - Altered diaphragm contractile properties with controlled mechanical ventilation.
21096827 - The pressure-volume relationship of the heart: past, present and future.
23194427 - Skinfold thickness as a predictor of arterial stiffness: obesity and fatness linked to ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  367     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-03-31     Completed Date:  1977-03-31     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  205-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Animals, Newborn / physiology*
Gestational Age
Pulmonary Alveoli / physiology*
Pulmonary Surfactants / pharmacology*
Residual Volume
Respiration / drug effects*
Surface Properties
Reg. No./Substance:
0/Pulmonary Surfactants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Retropsoas and subgluteal abscesses following paracervical and pudendal anesthesia.
Next Document:  The 2nd saccoradiculography: changes in the post-radiculographic and postoperative radiological morp...