Document Detail


Expanding the clinical and neuroradiological phenotype of 6q27 microdeletion: Olfactory bulb aplasia and anosmia.
MedLine Citation:
PMID:  21744487     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Subtelomeric deletions of chromosome 6q may result in a syndrome with brain malformations, comprising hydrocephalus and hypoplasia of the corpus callosum. Aplasia of the olfactory bulbs (OB) or anosmia has not been described in this syndrome. We describe a 3-year-old girl and a 25-year-old man with subtelomere 6q deletions. Both patients had aplastic OB and hydrocephalus. Subtelomeric 6q deletions might be underdiagnosed as anosmia can be the only symptom. © 2011 Wiley-Liss, Inc.
Authors:
J C Gerber; T M Neuhann; N Tyshchenko; M Smitka; K Hackmann
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-8
Journal Detail:
Title:  American journal of medical genetics. Part A     Volume:  -     ISSN:  1552-4833     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235741     Medline TA:  Am J Med Genet A     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Neuroradiology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany; Interdisciplinary Center for Smell and Taste, Otorhinolaryngology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany. johannes.gerber@uniklinikum-dresden.de.
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