Document Detail


Exophthalmos, pretibial myxedema, osteoarthropathy syndrome associated with papillary fibroelastoma in the left ventricle.
MedLine Citation:
PMID:  10646668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
EMO syndrome, a rare complication of Graves' disease, exhibits exophthalmos, pretibial myxedema, and osteoarthropathy. The presence of functional thyrotropin receptors (TSHR) in adipocytes and osteoblasts, both of which we have recently observed, may be related to these extrathyroidal manifestations of Graves' disease. In addition, the expression of TSHR in the heart has recently been reported. We describe here a patient with Graves' disease exhibiting EMO syndrome with a papillary fibroelastoma in the left ventricle. Pathological examinations showed that the fibroelastoma contained Alcian blue-stained mucinous materials that were also observed in the subcutaneous tissue of pretibial myxedema.
Authors:
H Suzuki; H Shimura; K Haraguchi; N Harii; T Endo; S Hosaka; S Yoshii; Y Tada; T Onaya
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  9     ISSN:  1050-7256     ISO Abbreviation:  Thyroid     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-03     Completed Date:  2000-02-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1257-60     Citation Subset:  IM    
Affiliation:
The Third Department of Internal Medicine, Yamanashi Medical University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Fibroma / complications*,  pathology
Graves Disease / complications*
Heart Neoplasms / complications*,  pathology
Heart Ventricles
Humans
Leg Dermatoses / complications*,  pathology
Male
Middle Aged
Myxedema / complications*
Osteoarthropathy, Secondary Hypertrophic / etiology*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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