Document Detail


Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila.
MedLine Citation:
PMID:  8982339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exophilin A, a new antibacterial compound, was discovered in the culture of the marine microorganism Exophiala pisciphila NI10102, which was isolated from a marine sponge Mycale adhaerens. The absolute chemical structure of exophilin A was elucidated as a trimer of (3R,5R)-3,5-dihydroxydecanoic acid by spectroscopic methods and analyses of a degradative product. Exophilin A showed antimicrobial activity against Gram-positive bacteria.
Authors:
J Doshida; H Hasegawa; H Onuki; N Shimidzu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of antibiotics     Volume:  49     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-01-27     Completed Date:  1997-01-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1105-9     Citation Subset:  IM    
Affiliation:
Central Research Laboratory, Nippon Suisan Kaisha, Ltd., Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / chemistry,  isolation & purification*,  pharmacology
Decanoates / chemistry,  isolation & purification,  pharmacology
Fermentation
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Decanoates; 0/exophilin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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