Document Detail

Exogenous ochronosis: case report and literature review.
MedLine Citation:
PMID:  22892783     Owner:  NLM     Status:  In-Data-Review    
Exogenous ochronosis is a rare, cosmetically disfiguring condition, resulting from the longterm use of topical hydroquinone in treatment of melasma. It manifests as gray-brown or blue-black macules in hydroquinone-exposed regions. The exact incidence of ochronosis is unknown. High rates have been reported in the South African population, and it is rare in the United States. We report the case of a patient who developed exogenous ochronosis while using topical hydroquinone. It is necessary to recognize this disorder at the earliest stage and discontinue hydroquinone immediately, as its treatment is difficult. Sun exposure facilitates the formation of exogenous ochronosis and must be strictly avoided, although it is a practical problem in the tropical climate of Brazil, particularly for those who work outdoors.
Viviane Maria Rocha Martins; Antônio Renê Diógenes de Sousa; Natália de Carvalho Portela; Celina Aguiar Frota Tigre; Lucidi Maria Saraiva Gonçalves; Rômulo José de Lucena Castro Filho
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anais brasileiros de dermatologia     Volume:  87     ISSN:  1806-4841     ISO Abbreviation:  An Bras Dermatol     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0067662     Medline TA:  An Bras Dermatol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  633-6     Citation Subset:  IM    
Dermatology Center Dona Libânia, Fortaleza, CE, Brazil.
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