| Exocrine pancreatic function as determined in a same-day test with use of bentiromide and p-aminosalicylic acid. | |
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MedLine Citation:
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PMID: 3486726 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a new approach to the bentiromide test of exocrine pancreatic function, p-Aminosalicylic acid (PAS), a compound closely related to the bentiromide fragment p-aminobenzoic acid (PABA), is used as a marker of the pharmacokinetic behavior of PABA to derive a PABA excretion index. This index is identical to that derived with [14C]-PABA. Concentrations of both PABA and PAS are measured in urine by "high-performance" liquid chromatography, which avoids the drug interferences encountered with established assays of PABA. We discuss the practical and diagnostic advantages of this new approach to the bentiromide test. |
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Authors:
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J D Berg; I M Chesner; R A Allen-Narker; B M Buckley; N Lawson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical chemistry Volume: 32 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-07-03 Completed Date: 1986-07-03 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1010-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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4-Aminobenzoic Acid
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analogs & derivatives,
diagnostic use*,
metabolism,
urine Adult Aminobenzoic Acids / diagnostic use* Aminosalicylic Acid / diagnostic use*, metabolism, urine Aminosalicylic Acids / diagnostic use* Female Humans Kinetics Male Middle Aged Pancreas / physiology* Pancreatic Function Tests* |
| Chemical | |
Reg. No./Substance:
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0/Aminobenzoic Acids; 0/Aminosalicylic Acids; 150-13-0/4-Aminobenzoic Acid; 37106-97-1/bentiromide; 65-49-6/Aminosalicylic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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