| Existing and emerging therapies for irritable bowel syndrome. | |
| | |
MedLine Citation:
|
PMID: 21438740 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Introduction: Irritable bowel syndrome is a common disorder that is associated with a significant impact on both affected individuals and society. While the pathophysiology of irritable bowel syndrome remains unknown, knowledge regarding the normal and abnormal functions of the gut and its complex interaction with the body's nervous systems continues to shed light on the multifactorial origins of irritable bowel syndrome symptoms. This article provides an overview of the current knowledge of the therapeutic approaches to irritable bowel syndrome. Areas covered: A search of the online bibliographic databases MEDLINE and EMBASE was performed in order to identify all relevant articles published between 1980 and 2010. The search was enhanced with the use of a medical librarian. Bibliographies from potentially relevant articles were manually searched. Expert opinion: The therapeutic options for irritable bowel syndrome are rapidly evolving beyond traditional symptom-based therapies, such as fiber, antispasmodics, antidiarrheals and laxatives, and are moving toward agents with organ-specific receptor selectivity directed, in many cases, at specific gastrointestinal functions. |
| | |
Authors:
|
Ruben D Acosta; Brooks D Cash |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-26 |
Journal Detail:
|
Title: Expert opinion on emerging drugs Volume: - ISSN: 1744-7623 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101135662 Medline TA: Expert Opin Emerg Drugs Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
National Naval Medical Center and Walter Reed Army Medical Center, Division of Gastroenterology, 8901 Wisconsin Avenue, Bethesda, MD 20889-5000, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Historical perspective on the use of animal bioassays to predict carcinogenicity: Evolution in desig...
Next Document: Opportunities and challenges of the pulmonary route for vaccination.