Document Detail

Existence of subtypes of gustducin-immunoreactive cells in the vallate taste bud of guinea pigs.
MedLine Citation:
PMID:  18431029     Owner:  NLM     Status:  MEDLINE    
Vallate taste buds in the guinea-pig tongue were immunohistochemically investigated with regard to the colocalization of gustducin with calbindin-D28K (=spot 35 protein) and type III inositol triphosphate receptor (IP(3)R-3) in order to characterize gustducin-immunoreactive cells. Individual taste bud cells ranged from totally immunopositive to totally immunonegative for these three molecules. Among the immunoreactive cells, gustducin-immunoreactive cells were divided into two cell populations: one immunopositive and the other immunonegative for calbindin-D28K. Applying our previous data to the present results, the former cells should belong to Type III cells designated by electron microscopy. This finding provides new evidence regarding the taste bud types of cells expressing gustducin in the guinea pig.
Yasuhiro Ohkubo; Hiroyuki Yokosuka; Masahiko Kumakura; Sumio Yoshie
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of histology and cytology     Volume:  70     ISSN:  0914-9465     ISO Abbreviation:  Arch. Histol. Cytol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-04-23     Completed Date:  2008-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806082     Medline TA:  Arch Histol Cytol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  291-6     Citation Subset:  IM    
Department of Histology, Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.
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MeSH Terms
Calcium-Binding Protein, Vitamin D-Dependent / metabolism
Guinea Pigs
Inositol 1,4,5-Trisphosphate Receptors / metabolism
Taste Buds / cytology*,  immunology,  metabolism*
Transducin / immunology*,  metabolism*
Reg. No./Substance:
0/Calcium-Binding Protein, Vitamin D-Dependent; 0/Inositol 1,4,5-Trisphosphate Receptors; 0/calbindin; 147979-21-3/Gnat3 protein, rat; EC 3.6.1.-/Transducin

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