Document Detail

Existence and severity of nausea and vomiting in pregnancy (NVP) with different partners.
MedLine Citation:
PMID:  17654185     Owner:  NLM     Status:  MEDLINE    
Nausea and vomiting in pregnancy (NVP) is a widespread condition which may impact on the quality of life. Our objective was to understand the role of the placenta, which is mostly made up of fetal cells, in NVP. We examined the relationship between NVP and different partners in the same women. If a paternal contribution to placental function affects NVP, this could shed light on the genetics of the most common condition in pregnancy. We assessed nausea and vomiting in two groups of 100 women counselled by the Motherisk Program in Toronto, using a score from 1 (none) to 5 (severe with hyperemesis). The first group had >/=2 pregnancies with the same partner; the second had >/=2 pregnancies with >/=2 partners. Scores were averaged across pregnancies, partners and overall. Regression was used to separate numbers of pregnancies and partners. The 100 women having one partner reported an average score of 3.1 in their 261 pregnancies, which was similar to the score of 3.0 in 319 multi-partner pregnancies (p = 0.508). There was a positive (but weak) correlation between gravidity and NVP score (Spearman's rho = 0.21, p < 0.001) but not between partner and score. There was a linear increase in scores from 2.7 in the first pregnancy, to 4.0 in the tenth (rho = 0.948, p < 0.01). After controlling for number of pregnancies, number of partners was not associated with NVP scores (p = 0.302). NVP severity tends to increase with each successive pregnancy. Different partners have no impact on NVP severity.
T R Einarson; Y Navioz; C Maltepe; A Einarson; G Koren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  27     ISSN:  0144-3615     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-07-26     Completed Date:  2007-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  360-2     Citation Subset:  IM    
Motherisk Program, Hospital For Sick Children, University of Toronto, Toronto, Canada.
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MeSH Terms
Morning Sickness*
Reproductive History*
Severity of Illness Index
Sexual Partners*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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