Document Detail


Exhaustive exercise, animal stress, and environmental hypercapnia on motility of sperm of steelhead trout (Oncorhynchus mykiss).
MedLine Citation:
PMID:  17303460     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Motility of salmonid sperm is inhibited by the presence of carbon dioxide (CO2) in vitro; however, whether this occurs in response to challenges to the adult in vivo is not known. To determine whether CO2 negatively impacts sperm function in vivo, mature males were exposed to exhaustive exercise as well as to acute stress, chronic stress, tricaine anesthesia and environmental hypercapnia and sperm motility and semen CO2 tensions and pH values assessed. Semen CO2 rose and pH decreased significantly only in response to exhaustive exercise and environmental hypercapnia (13 kPa CO2). These changes in semen CO2 and pH were associated with reductions in numbers of sperm becoming motile upon water activation. Chronic and acute stress and tricaine anesthesia were without effect on sperm motility or on semen CO2 or pH. The time course of CO2 inhibition and recovery was evaluated in vitro. At least 50 min was required to note 50% of the inhibitory effect of low CO2 tensions on motility when sperm were exposed to 1.6-3.1 kPa CO2. At higher CO2 levels sperm motility displayed 50% of the inhibitory effect of these tensions within about 30 min. Sperm recovered maximal motility within 1 h of being placed in a nominally CO2-free environment. This study demonstrates sperm vulnerability to not only in vitro CO2 exposure but also in vivo exposure during exhaustive exercise and as result of environmental hypercapnia.
Authors:
Micah D Zuccarelli; Rolf L Ingermann
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2007-01-16
Journal Detail:
Title:  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology     Volume:  147     ISSN:  1095-6433     ISO Abbreviation:  Comp. Biochem. Physiol., Part A Mol. Integr. Physiol.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-03-30     Completed Date:  2007-06-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9806096     Medline TA:  Comp Biochem Physiol A Mol Integr Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-53     Citation Subset:  IM    
Affiliation:
Department of Biological Sciences and Center for Reproductive Biology, University of Idaho, Moscow, ID 83844-3051, USA.
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MeSH Terms
Descriptor/Qualifier:
Acetazolamide / pharmacology
Animals
Carbon Dioxide / blood,  pharmacology
Environment*
Hydrogen-Ion Concentration / drug effects
Hypercapnia / chemically induced,  pathology*
Oncorhynchus mykiss / physiology*
Physical Conditioning, Animal / physiology*
Semen / drug effects,  metabolism
Sperm Motility / drug effects,  physiology*
Stress, Physiological / physiopathology*
Time Factors
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide; 59-66-5/Acetazolamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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