Document Detail

Exhaled breath condensate pH is increased after moderate exercise.
MedLine Citation:
PMID:  17388749     Owner:  NLM     Status:  MEDLINE    
Exhaled breath condensate (EBC) of patients with inflammatory diseases has a decreased pH. This could make EBC-pH an interesting tool for studying work-related inflammatory processes, provided that normal work activities would not interfere with the results. We consequently tested whether EBC-pH was influenced by moderate exercise. Fifteen healthy nonsmoking subjects exercised for 30 min on a treadmill by walking at 60% of predicted maximal heart rate. Four EBC samples were obtained: one to learn the technique, one before exercise, one immediately after exercise, and one 60 min later. EBC-pH was significantly increased after exercise compared to before (mean of 8.27 vs. 8.20, p = 0.001). It remained significantly increased after 60 min (8.25, p = 0.02). The increase was strongest for the subjects with lowest pH. All pH measures were significantly correlated with each other. Light physical activity increases EBC-pH. The persistence of this increase after the end of the exercise poses a serious challenge if one wants to use this technique for health surveys or for diagnostic purposes. It could prevent the observation of a lowered EBC-pH that results from an inflammatory response.
Michael Riediker; Brigitta Danuser
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine     Volume:  20     ISSN:  0894-2684     ISO Abbreviation:  J Aerosol Med     Publication Date:  2007  
Date Detail:
Created Date:  2007-03-28     Completed Date:  2007-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809251     Medline TA:  J Aerosol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  13-8     Citation Subset:  T    
Institute for Occupational Health Sciences, Lausanne, Switzerland.
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MeSH Terms
Breath Tests
Exercise / physiology*
Exercise Test
Exhalation / physiology*
Follow-Up Studies
Heart Rate / physiology
Hydrogen-Ion Concentration
Reproducibility of Results
Walking / physiology
Reg. No./Substance:

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