Document Detail

Exhaled breath condensate pH in the evaluation of asthma.
MedLine Citation:
PMID:  18302839     Owner:  NLM     Status:  MEDLINE    
As a marker of inflammation, exhaled breath condensate (EBC) pH may be a useful screening tool in the evaluation of asthma, especially in a military recruit population. To evaluate the utility of EBC pH in the diagnosis of asthma, EBC pH levels were determined in basic military trainees prior to an evaluation for asthma that included a history, physical exam, baseline spirometry, and a methacholine or exercise challenge. Of 86 basic trainees who had symptoms suggestive of asthma and underwent methacholine or exercise challenges, 51 (59.3%) had a positive methacholine or exercise challenge and were diagnosed with asthma. The mean EBC pH of the trainees who were diagnosed with asthma (6.39, range 5.91-6.82), was significantly (p < 0.001) lower than those trainees without asthma (6.64, range 6.34-7.18). There was, however, some overlap of the EBC pH values between the two groups. The measurement of EBC pH did show a significant mean difference between asthmatic and nonasthmatic patients in a military recruit population.
Christopher Coop; Larry L Hagan; John P Dice
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Allergy and asthma proceedings : the official journal of regional and state allergy societies     Volume:  29     ISSN:  1088-5412     ISO Abbreviation:  Allergy Asthma Proc     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9603640     Medline TA:  Allergy Asthma Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
59 Medical Wing/MMIA, Lackland AFB, Texas 78236-2300, USA.
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MeSH Terms
Asthma / diagnosis*,  physiopathology
Biological Markers / analysis
Breath Tests*
Bronchial Provocation Tests
Bronchoconstrictor Agents / diagnostic use
Exercise Test
Forced Expiratory Volume
Hydrogen-Ion Concentration*
Methacholine Chloride / diagnostic use
Military Personnel
Vital Capacity
Reg. No./Substance:
0/Biological Markers; 0/Bronchoconstrictor Agents; 62-51-1/Methacholine Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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