| Exfoliative cytology of the oral mucosa in burning mouth syndrome: a cytomorphological and cytomorphometric analysis. | |
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MedLine Citation:
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PMID: 19702671 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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doi:10.1111/j.1741-2358.2009.00319.x Exfoliative cytology of the oral mucosa in burning mouth syndrome: a cytomorphological and cytomorphometric analysis Objective: The aim of this study was to evaluate oral epithelial cells by exfoliative cytology in burning mouth syndrome (BMS). Material and methods: Oral smears were collected from clinically normal-appearing mucosa by liquid-based exfoliative cytology in 40 individuals (20 BMS patients and 20 healthy controls matched for age and gender) and analysed for cytological and cytomorphometric techniques. Results: Mean values of nuclear area (NA) for experimental and control groups were, respectively, 67.52 and 55.64 μm(2) (p < 0.05). Cytoplasmic area (CA) showed the following mean values: 1258.0 (experimental) and 2069.0 μm(2) (control). Nucleus-to-cytoplasm area ratio for the experimental group was 0.07, besides the control group was 0.03 (p < 0.05). Morphologically, oral smears exhibited normal epithelial cells in both experimental and control groups. There was a significant predominance of nucleated cells of the superficial layer in the smears of BMS patients (p = 0.00001). Conclusion: This study revealed that oral mucosa of BMS patients exhibited significant cytomorphometric changes in the oral epithelial cells. These changes probably are associated with epithelial atrophy and a deregulated maturation process that may contribute to the oral symptoms of pain and discomfort in BMS. |
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Authors:
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Talita Wandeur; Sérgio Adriane Bezerra de Moura; Ana Miryam Costa de Medeiros; Maria Ângela Naval Machado; Luciana Reis de Azevedo Alanis; Ana Maria Trindade Grégio; Paula Cristina Trevilatto; Antonio Adilson Soares de Lima |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gerodontology Volume: 28 ISSN: 1741-2358 ISO Abbreviation: Gerodontology Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8215850 Medline TA: Gerodontology Country: England |
Other Details:
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Languages: eng Pagination: 44-8 Citation Subset: D |
Copyright Information:
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© 2010 The Gerodontology Society and John Wiley & Sons A/S. |
Affiliation:
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Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil Department of Anatomy, School of Dentistry, Universidade Federal de Campina Grande, Cuité, Paraíba, Brazil Department of Oral Diagnosis, School of Dentistry, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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