Document Detail

Exertional hemodynamics in women with chest pain--an aortic Doppler ultrasound study.
MedLine Citation:
PMID:  8358881     Owner:  NLM     Status:  MEDLINE    
Aortic ultrasound Doppler recordings of stroke volume, maximal flow velocity, and acceleration can be used to assess central hemodynamic effects of exercise in coronary artery disease (CAD) and left ventricular dysfunction. We wanted to evaluate the time course and amplitude of changes in aortic Doppler ultrasound parameters in women during supine exercise and the potential diagnostic value of a submaximal supine exercise test. For this purpose, 18 women who had undergone coronary angiography because of incapacitating chest pain (10 with significant coronary stenoses and previous myocardial infarction, 8 without stenoses or infarction) were compared with 10 healthy controls. Pathological electrocardiographic (ECG) ST-segment depression during supine exercise was common in all groups. In the control group, a significant increase of stroke volume (10%), maximal aortic flow velocity (27%), and acceleration (43%) occurred at low load during exercise. Women with CAD showed no increase and a lower cardiac output during exercise, indicating left ventricular dysfunction. Women with syndrome X resembled the controls but had a higher maximal flow velocity at rest, which may indicate hyperdynamic circulation. We conclude that a test up to 40% of seated maximal load is valuable and often sufficient when assessing the hemodynamic effects of supine exercise by Doppler ultrasound in terms of stroke volume, maximal flow velocity, and acceleration. By characterizing left ventricular function in groups of female patients where false-positive stress ECG reactions are common, Doppler ultrasound may contribute to the understanding and clinical management of women with chest pain.
B J Sjöberg; E Swahn; B Wranne
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical cardiology     Volume:  16     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-09-27     Completed Date:  1993-09-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  480-6     Citation Subset:  IM    
Department of Clinical Physiology, Linköping Heart Center, University Hospital, Sweden.
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MeSH Terms
Angina Pectoris / physiopathology*,  ultrasonography*
Coronary Disease / physiopathology,  ultrasonography
Echocardiography, Doppler*
Exercise / physiology
Exercise Test / methods
Hemodynamics / physiology*
Middle Aged
Stroke Volume / physiology
Ventricular Function, Left / physiology

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