| Exercise without weight loss is an effective strategy for obesity reduction in obese individuals with and without Type 2 diabetes. | |
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MedLine Citation:
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PMID: 15860689 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is unclear whether chronic exercise without caloric restriction or weight loss is a useful strategy for obesity reduction in obese men with and without Type 2 diabetes (T2D). We examined the effects of exercise without weight loss on total and regional adiposity and skeletal muscle mass and composition in lean men and in obese men with and without T2D. Twenty-four men participated in 13 wk of supervised aerobic exercise, five times per week for 60 min at a moderate intensity (approximately 60% peak oxygen uptake). Total and regional body composition was measured by magnetic resonance imaging. Skeletal muscle composition was determined using computed tomography. Cardiorespiratory fitness was assessed using a graded maximal treadmill test. Body weight did not change within any group in response to exercise (P > 0.1). Significant reductions in total, abdominal subcutaneous, and visceral fat were observed within each group (P < 0.01). The reduction in total and abdominal subcutaneous fat was not different (P > 0.1) between groups; however, the reduction in visceral fat was greater (P < 0.01) in the obese and T2D groups by comparison to the lean group. A significant (P < 0.01) increase in total skeletal muscle, high-density muscle area, and mean muscle attenuation was observed independent of group, and these changes were not different between groups (P > 0.1). Accordingly, whole body fat-to-muscle ratio was increased (P < 0.01) independent of groups. In conclusion, regular exercise without weight loss is associated with a substantial reduction in total and visceral fat and in skeletal muscle lipid in both obesity and T2D. |
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Authors:
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SoJung Lee; Jennifer L Kuk; Lance E Davidson; Robert Hudson; Katherine Kilpatrick; Terry E Graham; Robert Ross |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2005-04-28 |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 99 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-08-16 Completed Date: 2005-10-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: United States |
Other Details:
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Languages: eng Pagination: 1220-5 Citation Subset: IM |
Affiliation:
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School of Physical and Health Education, Queen's Univ., Kingston, Ontario, Canada K7L 3N6. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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pathology Body Composition* Body Weight* Diabetes Mellitus, Type 2 / complications, physiopathology*, therapy* Exercise Therapy / methods* Humans Male Middle Aged Muscle, Skeletal / pathology Obesity / complications, physiopathology*, therapy* Organ Size Treatment Outcome Weight Loss* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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