Document Detail

Exercise vascular responses in health and disease.
MedLine Citation:
PMID:  9448897     Owner:  NLM     Status:  MEDLINE    
In normal subjects during exercise, there is vasoconstriction of non-exercise resistance vessels and an increase in blood pressure. We have investigated patients with vasovagal syncope with structurally normal hearts and patients with hypertrophic cardiomyopathy compared with normal controls and found a failure of vasoconstriction in both patients with vasovagal syncope and hypertrophic cardiomyopathy compared with normals and this has been associated with exercise hypotension. An association between exercise hypotension and sudden death has previously been reported in hypertrophic cardiomyopathy. We speculate that in patients with vasovagal syncope and structurally and electrically normal hearts, exercise hypotension is well tolerated, but in patients with structurally abnormal hearts, exercise hypotension can have catastrophic consequences.
H Thomson
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  27     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1998-03-18     Completed Date:  1998-03-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  459-61     Citation Subset:  IM    
Department of Cardiology, Prince Charles Hospital, Brisbane, Qld.
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MeSH Terms
Cardiomyopathy, Hypertrophic / physiopathology*
Exercise / physiology*
Exercise Test
Hypotension / etiology,  physiopathology
Predictive Value of Tests
Syncope, Vasovagal / physiopathology*
Vascular Resistance / physiology*
Vasoconstriction / physiology*

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