Document Detail


Exercise and the treatment of diabetes and obesity.
MedLine Citation:
PMID:  19026938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lifestyle intervention programs encompassing exercise and healthy diets are an option for the treatment and management of obesity and type 2 diabetes and have long been known to exert beneficial effects on whole-body metabolism, in particular leading to enhanced insulin-sensitivity. Obesity is associated with increased risk of several illnesses and premature mortality. However, physical inactivity is itself associated with a number of similar risks, independent of body-mass index, and is an independent risk factor for more than 25 chronic diseases, including type 2 diabetes and cardiovascular disease. This article addresses the debate regarding the relative effects of physical exercise itself and the effect of exercise-induced weight loss.
Authors:
Donal J O'Gorman; Anna Krook
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Endocrinology and metabolism clinics of North America     Volume:  37     ISSN:  1558-4410     ISO Abbreviation:  Endocrinol. Metab. Clin. North Am.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800104     Medline TA:  Endocrinol Metab Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  887-903     Citation Subset:  IM    
Affiliation:
School of Health and Human Performance, Dublin City University, Dublin, Ireland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Diabetes Mellitus / genetics,  metabolism,  therapy*
Exercise / physiology
Exercise Therapy* / methods
Gene Expression Regulation / physiology
Genetic Variation / physiology
Humans
Muscle Contraction / genetics
Muscle, Skeletal / metabolism,  physiology
Obesity / genetics,  metabolism,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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