Document Detail

Exercise training reverses exertional oscillatory ventilation in heart failure patients.
MedLine Citation:
PMID:  22408198     Owner:  NLM     Status:  Publisher    
Exertional oscillatory ventilation (EOV) is an ominous prognostic sign in chronic heart failure (CHF), but little is known about the success of specific therapeutic interventions.To study the impact of an exercise training on exercise capacity and cardiopulmonary adaptation in stable CHF patients with left ventricular systolic dysfunction and EOV.96 stable CHF patients with EOV were included in a retrospective analysis (52 training vs. 44 controls). EOV was defined as follows: (1) ≥3 oscillatory fluctuations in VE during exercise; (2) regular oscillations; (3) minimal average ventilation amplitude ≥5 litres.EOV disappeared in 37/52 (71.2%) patients after training but only in 1/44 (2.3%) without training (p<0.001). The decrease of EOV amplitude correlated with changes in PETCO2 (r= -0.60, p<0.001) at the respiratory compensation point (RCP) and VE/VCO2 slope (r=0.50, p<0.001). Training significantly improved resting values of breathing frequency (BF), ventilation (VE), tidal volume (VT) and VE/VCO2 ratio. During exercise, VE and VT reached significantly higher values at the peak, while BF and VE/VCO2 ratio were significantly lower at submaximal exercise. No change was noted in the control group.Exercise training leads to a significant decrease of EOV and improves ventilatory efficiency in patients with stable CHF.
Marzena Zurek; Ugo Corrà; Massimo F Piepoli; Ronald K Binder; Hugo Saner; Jean-Paul Schmid
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-9
Journal Detail:
Title:  The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology     Volume:  -     ISSN:  1399-3003     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Dept of Cardiology, Bern University Hospital, and University of Bern, Bern, Switzerland.
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