Document Detail

Exercise training raises daily activity stronger than predicted from exercise capacity in patients with COPD.
MedLine Citation:
PMID:  15878487     Owner:  NLM     Status:  MEDLINE    
The 6-min walking (6MWD) and 6-min treadmill distance (6MTD) are often used as measures of exercise performance in patients with COPD. The aim of our study was to assess their relationship to daily activity in the course of an exercise training program. Eighty-eight patients with stable COPD (71m/17f; mean +/- SD age, 60 +/-8 year; FEV1, 43+/-14% pred) were recruited, 66 of whom performed a hospital-based 10-day walking training, whereas 22 were treated as control. On day 16MTD, and on days 8 and 10, 6MTD and 6MWD were determined. In addition, patients used an accelerometer (TriTrac-R3D) to record 24 h-activity, whereby training sessions were excluded. In both groups there was a linear relationship (r > or = 0.84 and P < 0.0001) between 6MTD and 24 h-activity, the slope of which was 2.5-fold greater in the training group (P < 0.01). Similar relationships emerged for 6MWD. There was no association between baseline 6MTD, FEV1 or BMI and any of the other measures. These data suggest that daily activity did not markedly vary with exercise capacity under baseline conditions. Participation in a training program increased activity significantly stronger than predicted from the gain in exercise capacity. This underlines the importance of non-physiological, patient-centered factors associated with training in COPD.
Michaela Behnke; Alexandra R Wewel; Detlef Kirsten; Rudolf A Jörres; Helgo Magnussen
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Publication Detail:
Type:  Journal Article     Date:  2005-01-18
Journal Detail:
Title:  Respiratory medicine     Volume:  99     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-09     Completed Date:  2005-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  711-7     Citation Subset:  IM    
Hospital Grosshansdorf, Centre for Pneumology and Thoracic Surgery, Woehrendamm 80, D-22927 Grosshansdorf, Germany.
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MeSH Terms
Activities of Daily Living*
Case-Control Studies
Exercise Test
Exercise Therapy / methods*
Middle Aged
Physical Fitness
Pulmonary Disease, Chronic Obstructive / physiopathology*,  therapy

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