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Exercise training in patients with pulmonary arterial hypertension: a case report.
MedLine Citation:
PMID:  20467524     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe the benefits of a feasible, outpatient exercise training program on exercise tolerance and health-related quality of life (HRQL) in individuals with pulmonary arterial hypertension (PAH).
METHODS: Case report on two subjects recruited from a tertiary care pulmonary hypertension clinic. Subject 1 was a 50-year-old male with idiopathic PAH. Subject 2 was a 54-year-old female with a 20+ year history of scleroderma and 6-year history of PAH. Both subjects underwent exercise training 3 times per week for 6 weeks using a cycle ergometer at workloads progressing from 50% to 80% of peak workload. Outcomes were assessed using cardiopulmonary exercise testing, six-minute walk test (6MWT), and HRQL using the Chronic Respiratory Disease Questionnaire (CRQ) and the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR).
RESULTS: Both subjects made substantial improvements in oxygen consumption and workload at anaerobic threshold (improvements of 3.8 and 4.2 mL.kg(-1).min,(-1) 26 and 18 W, respectively) and 6MWT distance (from 496 to 586m and 416 to 517m, respectively). Only Subject 1 made substantial improvements in peak oxygen consumption (from 16.0 to 18.3 mL.kg(-1).min(-1)and from 15.0 to 15.6 mL.kg(-1).min,(-1) respectively) and peak work rate (from 112 to 130W and 66 to 69W, respectively). Both subjects demonstrated improved HRQL. No adverse events were noted.
CONCLUSIONS: A short and practical exercise training program can improve measures of workload, aerobic capacity, and HRQL in individuals with PAH with no adverse effects shown in these two case studies.
Authors:
Michael J Shoemaker; Jeffrey L Wilt; Rajkumar Dasgupta; Ronald J Oudiz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiopulmonary physical therapy journal     Volume:  20     ISSN:  1541-7891     ISO Abbreviation:  Cardiopulm Phys Ther J     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2011-07-14     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  101155626     Medline TA:  Cardiopulm Phys Ther J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  12-8     Citation Subset:  -    
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