Document Detail

Exercise training in patients receiving maintenance hemodialysis: a systematic review of clinical trials.
MedLine Citation:
PMID:  16088076     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Exercise is not routinely advocated in patients with end-stage renal disease (ESRD) receiving maintenance hemodialysis (HD), compared to best practice in other chronically diseased cohorts. Lack of widespread awareness of the exercise in HD literature may be contributing to these shortcomings of clinical practice. Therefore, our objectives are: (1) to systematically review trials of exercise training involving adult HD patients; (2) to provide empirical evidence that exercise can elicit health-related adaptations in this cohort, and (3) to provide recommendations for future investigations. METHOD: A systematic review of the literature using computerized databases was performed. RESULTS: According to the 29 trials reviewed, HD patients can safely derive a myriad of health-related adaptations from engaging in appropriately structured exercise regimens involving aerobic and/or resistance training. However, methodological limitations within this body of literature may be partially responsible for minimal advocacy for exercise in this cohort. CONCLUSIONS: Robustly designed RCTs with thorough, standardized reporting are required if clinical practice and quality of life of this cohort is to be enhanced through the integration of exercise training and mainstream medical practice. Future trials should demonstrate the clinical importance, and long-term feasibility and applicability of exercise training for this vulnerable patient population.
Birinder Singh B Cheema; Maria A Fiatarone Singh
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Publication Detail:
Type:  Journal Article; Review     Date:  2005-07-22
Journal Detail:
Title:  American journal of nephrology     Volume:  25     ISSN:  0250-8095     ISO Abbreviation:  Am. J. Nephrol.     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-08-16     Completed Date:  2005-11-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8109361     Medline TA:  Am J Nephrol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  352-64     Citation Subset:  IM    
Copyright Information:
Copyright 2005 S. Karger AG, Basel.
School of Exercise and Sport Science, University of Sydney, Australia.
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MeSH Terms
Adaptation, Physiological
Clinical Trials as Topic
Exercise Therapy / methods*
Kidney Failure, Chronic / physiopathology,  therapy*
Renal Dialysis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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