Document Detail


Exercise training in normobaric hypoxia in endurance runners. I. Improvement in aerobic performance capacity.
MedLine Citation:
PMID:  16540709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigates whether a 6-wk intermittent hypoxia training (IHT), designed to avoid reductions in training loads and intensities, improves the endurance performance capacity of competitive distance runners. Eighteen athletes were randomly assigned to train in normoxia [Nor group; n = 9; maximal oxygen uptake (VO2 max) = 61.5 +/- 1.1 ml x kg(-1) x min(-1)] or intermittently in hypoxia (Hyp group; n = 9; VO2 max = 64.2 +/- 1.2 ml x kg(-1) x min(-1)). Into their usual normoxic training schedule, athletes included two weekly high-intensity (second ventilatory threshold) and moderate-duration (24-40 min) training sessions, performed either in normoxia [inspired O2 fraction (FiO2) = 20.9%] or in normobaric hypoxia (FiO2) = 14.5%). Before and after training, all athletes realized 1) a normoxic and hypoxic incremental test to determine VO2 max and ventilatory thresholds (first and second ventilatory threshold), and 2) an all-out test at the pretraining minimal velocity eliciting VO2 max to determine their time to exhaustion (T(lim)) and the parameters of O2 uptake (VO2) kinetics. Only the Hyp group significantly improved VO2 max (+5% at both FiO2, P < 0.05), without changes in blood O2-carrying capacity. Moreover, T(lim) lengthened in the Hyp group only (+35%, P < 0.001), without significant modifications of VO2 kinetics. Despite similar training load, the Nor group displayed no such improvements, with unchanged VO2 max (+1%, nonsignificant), T(lim) (+10%, nonsignificant), and VO2 kinetics. In addition, T(lim) improvements in the Hyp group were not correlated with concomitant modifications of other parameters, including VO2 max or VO2 kinetics. The present IHT model, involving specific high-intensity and moderate-duration hypoxic sessions, may potentialize the metabolic stimuli of training in already trained athletes and elicit peripheral muscle adaptations, resulting in increased endurance performance capacity.
Authors:
Stéphane P Dufour; Elodie Ponsot; Joffrey Zoll; Stéphane Doutreleau; Evelyne Lonsdorfer-Wolf; Bernard Geny; Eliane Lampert; Martin Flück; Hans Hoppeler; Véronique Billat; Bertrand Mettauer; Ruddy Richard; Jean Lonsdorfer
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  100     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-16     Completed Date:  2007-01-04     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1238-48     Citation Subset:  IM    
Affiliation:
Département de Physiologie et des Explorations Fonctionnelles, Hôpital Civil, and Faculté de Médicine, Institut de Physiologie, Unité Propre de Recherche de l'Enseignement Supérieur Equipe d'Accueil, 3072 Strasbourg, France.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Adult
Anoxia / physiopathology*
Exercise Tolerance / physiology*
Humans
Kinetics
Male
Oxygen Consumption
Pulmonary Ventilation
Running*
Sports Medicine
Task Performance and Analysis
Comments/Corrections
Comment In:
J Appl Physiol (1985). 2007 Aug;103(2):730; author reply 731-2   [PMID:  17666736 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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