Document Detail

Exercise training in heart failure.
MedLine Citation:
PMID:  9872605     Owner:  NLM     Status:  MEDLINE    
Patients with heart failure challenge the clinician with a constellation of difficult clinical, pathophysiologic, and psychologic issues. As a result, until recently, exercise training was not considered a safe and effective treatment strategy to be used in these patients. However, in the past 10 years, data from both randomized and nonrandomized trials showed that regular exercise training in patients with stable Class II and III heart failure can safely improve exercise tolerance, attenuate an overactivated sympathetic nervous system, partially reverse skeletal muscle abnormalities, and enhance health-related quality of life. These outcomes are achievable with a relatively moderate dose of physical activity, such as 30 to 60 minutes of walking or cycling 3 to 5 days per week at an intensity equivalent to 60% to 70% of peak oxygen consumption. Sufficiently powered trials are needed to assess morbidity, mortality, and cost-effectiveness endpoints relative to exercise training in patients with heart failure.
A Afzal; C A Brawner; S J Keteyian
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  41     ISSN:  0033-0620     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  1999-01-07     Completed Date:  1999-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-90     Citation Subset:  AIM; IM; S    
Henry Ford Heart and Vascular Institute and Department of Internal Medicine, Detroit, MI, USA.
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MeSH Terms
Cardiac Output
Exercise / physiology*
Exercise Therapy*
Exercise Tolerance
Heart Failure / physiopathology,  therapy*
Hemodynamics / physiology
Muscle, Skeletal / physiopathology
Neurosecretory Systems / physiology
Pulmonary Ventilation / physiology
Quality of Life

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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