Document Detail

Exercise training improves selected aspects of daytime functioning in adults with obstructive sleep apnea.
MedLine Citation:
PMID:  22893765     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVES: To explore the utility of exercise training for improving daytime functioning in adults with obstructive sleep apnea (OSA).
METHODS: Forty-three sedentary and overweight/obese adults aged 18-55 years with at least moderate-severity untreated OSA (apnea-hypopnea index ≥ 15) were randomized to 12 weeks of moderate-intensity aerobic and resistance exercise training (n = 27) or low-intensity stretching control treatment (n = 16). As part of a trial investigating the efficacy of exercise training on OSA severity, daytime functioning was assessed before and following the intervention. Sleepiness, functional impairment due to sleepiness, depressive symptoms, mood, and quality of life (QOL) were evaluated with validated questionnaires, and cognitive function was assessed with a neurobehavioral performance battery. OSA severity was measured with one night of laboratory polysomnography before and following the intervention.
RESULTS: Compared with stretching control, exercise training resulted in significant improvements in depressive symptoms, fatigue and vigor, and aspects of QOL (p < 0.05). Sleepiness and functional impairment due to sleepiness also were improved following exercise versus control to a similar degree in terms of effect sizes (d > 0.5), though these changes were not statistically significant. No neurobehavioral performance improvements were found. Reduced fatigue following exercise training was mediated by a reduction in OSA severity, but changes in OSA severity did not significantly mediate improvement in any other measure of daytime functioning.
CONCLUSIONS: These data provide preliminary evidence that exercise training may be helpful for improving aspects of daytime functioning of adults with OSA. Larger trials are needed to further verify the observed improvements.
Christopher E Kline; Gary B Ewing; James B Burch; Steven N Blair; J Larry Durstine; J Mark Davis; Shawn D Youngstedt
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.     Date:  2012-08-15
Journal Detail:
Title:  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine     Volume:  8     ISSN:  1550-9397     ISO Abbreviation:  J Clin Sleep Med     Publication Date:  2012  
Date Detail:
Created Date:  2012-08-15     Completed Date:  2013-01-07     Revised Date:  2014-11-05    
Medline Journal Info:
Nlm Unique ID:  101231977     Medline TA:  J Clin Sleep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  357-65     Citation Subset:  IM    
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MeSH Terms
Activities of Daily Living
Depression / therapy
Exercise Therapy* / methods
Middle Aged
Neuropsychological Tests
Quality of Life
Resistance Training
Severity of Illness Index
Sleep Apnea, Obstructive / therapy*
Young Adult
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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