Document Detail

Exercise training and heart failure: a systematic review of current evidence.
MedLine Citation:
PMID:  11791816     Owner:  NLM     Status:  MEDLINE    
Chronic heart failure (CHEF) is a growing public health problem. Current guidelines provide detailed information regarding pharmacotherapy but little guidance about the value of exercise/cardiac rehabilitation programmes for individuals with this condition. To investigate the effects of exercise training upon CHF patients, a systematic literature review was carried out of trials (from 1966 to December 2000) which used as their main outcome measures the effects of exercise training upon: (a) physical performance; or (b) quality of life; or (c) morbidity/mortality. Databases searched include: MedLine; Science Citation Index; Social Sciences Citation Index; BIDS, Bandolier; Cochrane Database of Systematic Reviews (CDSR); NHS National Research Register (NRR); and Current Research in Britain (CRIB). Relevant bibliographic references from identified articles were also reviewed. Thirty-one trials were identified, comprising randomised controlled trials (RCTs) (14/31), randomised crossover trials (8/31), non-RCTs (2/31), and pre-test/post-test (7/31). Sample sizes were: 25 participants or fewer (20/31); 26 to 50 participants (7/31); 51 to 150 participants (4/31). Participants were predominantly younger with a mean age in 23/31 studies of 65 years or less, and male. Patients with comorbidities were often excluded. Positive effects were reported on physical performance (27/31), quality of life (11/16), mortality (1/31), and readmission rates (1/31). No cost-effectiveness analyses were identfied. We conclude that short-term physical exercise training in selected subgroups of patients with CHF has physiological benefits and positive effects on quality of life. This review highlights the continuing problem of clinical trials that include participants who are not representative of the general population of CHF patients seen in primary care. Further investigation of the utility and applicability of exercise training is essential.
Ffion Lloyd-Williams; Frances S Mair; Maria Leitner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The British journal of general practice : the journal of the Royal College of General Practitioners     Volume:  52     ISSN:  0960-1643     ISO Abbreviation:  Br J Gen Pract     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-01-15     Completed Date:  2002-02-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9005323     Medline TA:  Br J Gen Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  47-55     Citation Subset:  IM    
Department of Primary Care, School of Health Sciences, University of Liverpool.
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MeSH Terms
Aged, 80 and over
Chronic Disease
Cross-Over Studies
Exercise Therapy / methods*
Heart Failure / rehabilitation*
Middle Aged
Physical Endurance / physiology
Quality of Life
Randomized Controlled Trials as Topic
Treatment Outcome
Comment In:
Br J Gen Pract. 2002 May;52(478):413-4   [PMID:  12014548 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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