Document Detail

Exercise training for heart failure patients improves respiratory muscle endurance, exercise tolerance, breathlessness, and quality of life.
MedLine Citation:
PMID:  12576906     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Increased respiratory muscle endurance and peak oxygen consumption (VO(2peak)) induced by respiratory muscle training support the relationship between respiratory muscle function and exercise capacity in patients with heart failure. This raises the question whether exercise-training results in increased respiratory muscle function contributing to an increased exercise tolerance, a decreased perception of breathlessness, and an improved quality of life. METHODS: Prospective cohort analysis was completed on 24 patients with New York Heart Association (NYHA) Class III heart failure [18 men, 6 women; aged = 64 (SD 7.9) years; percent ejection fraction (%EF) = 24.0 (SD 7.8)]. Maximal sustainable ventilatory capacity (MSVC), submaximal and peak exercise responses, perception of breathlessness, and quality of life were measured before (baseline) and after (end of study) 12 weeks of exercise training. RESULTS: As a result of exercise training, VO(2peak) (P=.01) and MSVC (P<.001) increased, with MSVC contributing to a larger proportion of the variability for VO(2peak) at study completion (r=0.57 vs 0.42). Although stroke volume did not increase beyond exercise at 25 W and did not change with exercise training, ventilation decreased during exercise (P<.05), perception of breathing difficulty (P<.05) was reduced, and quality of life was enhanced (P=.008). CONCLUSIONS: Despite no increase in cardiac output and stroke volume, respiratory muscle endurance improved with exercise training, contributing to increased exercise capacity, decreased breathlessness, and decreased perception of breathlessness. Practical implications can include less frequent rest periods and fatigue, greater confidence, maintenance of independence, and enhanced quality of life.
Timothy R McConnell; Jeffrey S Mandak; Jeffrey S Sykes; Henry Fesniak; Himadri Dasgupta
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cardiopulmonary rehabilitation     Volume:  23     ISSN:  0883-9212     ISO Abbreviation:  J Cardiopulm Rehabil     Publication Date:    2003 Jan-Feb
Date Detail:
Created Date:  2003-02-10     Completed Date:  2003-05-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8511296     Medline TA:  J Cardiopulm Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10-6     Citation Subset:  IM    
Department of Cardiology, Geisinger Medical Center, Danville, PA 17822-2160, USA.
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MeSH Terms
Analysis of Variance
Cohort Studies
Dyspnea / prevention & control*
Exercise Therapy*
Exercise Tolerance / physiology*
Heart Failure / diagnosis,  rehabilitation*
Heart Function Tests
Middle Aged
Oxygen Consumption / physiology
Physical Endurance
Prospective Studies
Quality of Life*
Respiratory Function Tests
Respiratory Muscles / physiology*
Sensitivity and Specificity
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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