| Exercise training decreases the growth hormone (GH) response to acute constant-load exercise. | |
| | |
MedLine Citation:
|
PMID: 9140905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To assess the influence of exercise training on the growth hormone (GH) response to acute exercise, six untrained males completed a 20-min, high-intensity, constant-load exercise test prior to and after 3 and 6 wk of training (the absolute power output (PO) during each test remained constant x PO = 182.5 +/- 29.5 W). Training increased (pre- vs post-training) oxygen uptake (VO2) at lactate threshold (1.57 +/- 0.33 L.min-1 vs 1.97 +/- 0.24 L.min-1 P < or = 0.05). VO2 at 2.5 mM blood lactate concentration ([HLa]) (1.83 +/- 0.38 L.min-1 vs 2.33 +/- 0.38 L.min-1, P < or = 0.05), and VO2peak (3.15 +/- 0.54 L.min-1 vs 3.41 +/- 0.47 L.min-1, P < or = 0.05). Power output at the lactate threshold (PO-LT) increased with training from 103 +/- 28 to 132 +/- 23W (P < or = 0.05). Integrated GH concentration (20 min exercise + 45 min recovery) (microgram.L-1 x min) after 3 wk (138 +/- 106) and 6 wk (130 +/- 145) were significantly lower (P < or = 0.05) than pre-training (238 +/- 145). Plasma epinephrine and norepinephrine responses to training were similar to the GH response (EPI-pre-training = 2447 +/- 1110; week 3 = 1046 +/- 144; week 6 = 955 +/- 322 pmol.L-1; P < or = 0.05; NE pre-training = 23.0 +/- 5.2; week 3 = 13.4 +/- 4.8; week 6 = 12.1 +/- 6.8 nmol.L-1; P < or = 0.05). These data indicate that the GH and catecholamine response to a constant-load exercise stimulus are reduced within the first 3 wk of exercise training and support the hypothesis that a critical threshold of exercise intensity must be reached to stimulate GH release. |
| | |
Authors:
|
A Weltman; J Y Weltman; C J Womack; S E Davis; J L Blumer; G A Gaesser; M L Hartman |
Related Documents
:
|
16886585 - Effect of a high-fat meal on the growth hormone response to exercise in children. 12665985 - Basal testicular testosterone production in endurance-trained men is suppressed. 8806925 - Hormonal and metabolic responses to electrically induced cycling during epidural anesth... 3091975 - Pharmacological evidence for a dual gabaergic regulation of growth hormone release in h... 11513445 - Electrophysiologic characteristics of ventricular extrastimulation-induced dissipation ... 10335765 - Effects of cardiac rehabilitation and exercise training on peak aerobic capacity and wo... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Medicine and science in sports and exercise Volume: 29 ISSN: 0195-9131 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 1997 May |
Date Detail:
|
Created Date: 1997-06-18 Completed Date: 1997-06-18 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 669-76 Citation Subset: IM; S |
Affiliation:
|
Department of Human Services, Curry School of Education, Charlottesville, VA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Epinephrine / blood Exercise / physiology* Human Growth Hormone / blood, physiology* Humans Lactic Acid / blood* Male Norepinephrine / blood Oxygen Consumption Prospective Studies Time Factors |
| Grant Support | |
ID/Acronym/Agency:
|
R01 AG 10997/AG/NIA NIH HHS; RR 00847/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
|
12629-01-5/Human Growth Hormone; 50-21-5/Lactic Acid; 51-41-2/Norepinephrine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aldosterone and vasopressin responses in the heat: hydration level and exercise intensity effects.
Next Document: Interpreting the relation between force and cross-sectional area in human muscle.