Document Detail


Exercise therapy in the management of dyspnea in patients with cancer.
MedLine Citation:
PMID:  22516976     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Dyspnea is a frequent, debilitating, and understudied symptom in cancer associated with poor prognosis and reduced health-related quality of life. The purpose of this study is to review the incidence, pathophysiology, and mechanisms of dyspnea in patients diagnosed with cancer. We also discuss the existing evidence supporting the efficacy of exercise therapy to complement traditional approaches to reduce the impact of this devastating symptom in persons with cancer.
RECENT FINDINGS: In other clinical populations presenting with dyspnea, such as chronic obstructive pulmonary disease, exercise therapy is demonstrated to be an efficacious strategy. In contrast, relatively few studies to date have investigated the efficacy of exercise training as a therapeutic strategy to mitigate dyspnea in patients with cancer.
SUMMARY: Although much more work is required, exercise therapy is a promising adjunct strategy to systematically reduce dyspnea in the oncology setting that may also provide additive efficacy when prescribed in combination with other adjunct therapies including pharmacologic interventions.
Authors:
Graeme J Koelwyn; Lee W Jones; Whitney Hornsby; Neil D Eves
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in supportive and palliative care     Volume:  6     ISSN:  1751-4266     ISO Abbreviation:  Curr Opin Support Palliat Care     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-04     Completed Date:  2012-09-05     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101297402     Medline TA:  Curr Opin Support Palliat Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  129-37     Citation Subset:  IM    
Affiliation:
Integrative Clinical Cardiopulmonary Physiology Laboratory, Faculty of Health and Social Development, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
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MeSH Terms
Descriptor/Qualifier:
Dyspnea / drug therapy*,  etiology,  physiopathology,  rehabilitation*
Exercise Therapy / methods*
Humans
Incidence
Neoplasms / complications*
Pulmonary Disease, Chronic Obstructive / complications
Grant Support
ID/Acronym/Agency:
CA125458/CA/NCI NIH HHS; CA133895/CA/NCI NIH HHS; CA138634/CA/NCI NIH HHS; CA142566/CA/NCI NIH HHS; CA143254,/CA/NCI NIH HHS; R01 CA138624/CA/NCI NIH HHS; R01 CA142566/CA/NCI NIH HHS; R21 CA125458/CA/NCI NIH HHS; R21 CA133895/CA/NCI NIH HHS; R21 CA143254/CA/NCI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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