Document Detail

Exercise stress testing in children with metabolic or neuromuscular disorders.
MedLine Citation:
PMID:  20706686     Owner:  NLM     Status:  In-Data-Review    
The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.
Tim Takken; Wim G Groen; Erik H Hulzebos; Cornelia G Ernsting; Peter M van Hasselt; Berthil H Prinsen; Paul J Helders; Gepke Visser
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Publication Detail:
Type:  Journal Article     Date:  2010-07-15
Journal Detail:
Title:  International journal of pediatrics     Volume:  2010     ISSN:  1687-9759     ISO Abbreviation:  Int J Pediatr     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101517077     Medline TA:  Int J Pediatr     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The Netherlands.
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