Document Detail

Exercise and reproductive dysfunction.
MedLine Citation:
PMID:  9935107     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To provide an overview of our current understanding of exercise-induced reproductive dysfunction and an approach to its evaluation and management. DESIGN: A MEDLINE search was performed to review all articles with title words related to menstrual dysfunction, amenorrhea, oligomenorrhea, exercise, and athletic activities from 1966 to 1998. The pathophysiology, proposed mechanisms, clinical manifestations, evaluation, and management of exercise-associated reproductive dysfunction were compiled. CONCLUSION(S): Exercise-induced menstrual irregularity appears to be multifactorial in origin and remains a diagnosis of exclusion. The underlying mechanisms are mainly speculative. Clinical manifestations range from luteal phase deficiency to anovulation, amenorrhea, and even delayed menarche. Evaluation should include a thorough history and a complete physical plus pelvic examination. Most cases are reversible with dietary and exercise modifications. Hormonal replacement in cases of a prolonged hypoestrogenic state with evidence of increased bone loss is recommended, although the long-term consequences of prolonged hormonal deficiency are ill-defined.
E C Chen; R G Brzyski
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Fertility and sterility     Volume:  71     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-02-23     Completed Date:  1999-02-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio 78284, USA.
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MeSH Terms
Exercise / physiology*
Hormone Replacement Therapy
Infertility, Female / physiopathology*
Menstruation / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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