Document Detail

Exercise rehabilitation for the patient with intermittent claudication: a highly effective yet underutilized treatment.
MedLine Citation:
PMID:  15379615     Owner:  NLM     Status:  MEDLINE    
Peripheral arterial disease (PAD), when accompanied by claudication, is a disabling disease that affects 12 percent of the population of the United States (US). PAD is associated with increased mortality as well as decreased functional status and quality of life. Smoking cessation and treatment of diabetes are key aspects of risk factor modification for the PAD patient as well as controlling other cardiovascular risk factors. Typically, only the most severely diseased patients with PAD receive surgery for the indication of claudication and other therapeutic options are being sought. Exciting developments are taking place in the area of drug development for instance. The benefits of a supervised walking exercise program have been consistently demonstrated in persons with PAD and therefore, exercise rehabilitation constitutes an important form of therapy for these persons. Unfortunately, in the US, exercise rehabilitation is not always reimbursed which may lessen its utility presently. All therapies which are used to treat claudication should incorporate measures of functional status and quality of life in addition to treadmill walking in order to ascertain the benefit of a given treatment for patients with PAD.
Judith G Regensteiner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current drug targets. Cardiovascular & haematological disorders     Volume:  4     ISSN:  1568-0061     ISO Abbreviation:  Curr Drug Targets Cardiovasc Haematol Disord     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-21     Completed Date:  2005-03-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101123341     Medline TA:  Curr Drug Targets Cardiovasc Haematol Disord     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  233-9     Citation Subset:  IM    
Section of Vascular Medicine, Divisions of Internal Medicine and Cardiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.
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MeSH Terms
Clinical Trials as Topic
Exercise Therapy*
Intermittent Claudication / etiology,  physiopathology,  rehabilitation*
Peripheral Vascular Diseases / complications,  epidemiology,  rehabilitation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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