Document Detail

Exercise and physical therapy in early management of Parkinson disease.
MedLine Citation:
PMID:  22045326     Owner:  NLM     Status:  MEDLINE    
Experimental research has produced evidence in recent years underlying the beneficial effects that exercise can have in preventing and deceleration of the development of Parkinson disease. These beneficial effects are exerted through various mechanisms such as neuroprotection, neurotransmission, plasticity, neurogenesis, homeostasis, and neurotrophic factors. Studies on clinical application at an early stage are still scarce, although some results are encouraging. There are still many questions to determine the most suitable type of exercise (forced/voluntary), the time of its implementation, the duration, and the combination of strategies. Nonconventional therapies can play an important role in addition to exercise, and are so numerous that they could be adapted to the circumstances of patients, although there is no evidence to date that they could have a neuroprotective effect.
Fernando Alonso-Frech; Juan Juni Sanahuja; Amelia Mendoza Rodriguez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The neurologist     Volume:  17     ISSN:  2331-2637     ISO Abbreviation:  Neurologist     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-02     Completed Date:  2012-02-21     Revised Date:  2014-11-05    
Medline Journal Info:
Nlm Unique ID:  9503763     Medline TA:  Neurologist     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S47-53     Citation Subset:  IM    
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MeSH Terms
Clinical Trials as Topic
Disease Management*
Parkinson Disease / physiopathology,  therapy*
Physical Therapy Modalities*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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