Document Detail

Exercise performance in patients with hypertension. Relation to electrocardiographic criteria for left ventricular hypertrophy.
MedLine Citation:
PMID:  2137511     Owner:  NLM     Status:  MEDLINE    
The influence of the electrocardiographic diagnosis of left ventricular hypertrophy on exercise performance was assessed in 101 hypertensive patients and 37 control subjects referred to an exercise testing laboratory. Maximal exercise capacity was measured by the duration of a symptom-limited, treadmill test using the modified Bruce protocol. The Romhilt-Estes point score system, as modified by Murphy, was used to define left ventricular hypertrophy by electrocardiographic criteria. After adjusting for age differences between hypertensive and control subjects, the hypertensive group without left ventricular hypertrophy had a shorter exercise duration than the control group (13.0 +/- 3.0 vs. 15.3 +/- 2.5 min, respectively; p less than 0.01). The 16 hypertensive patients with electrocardiographic evidence of hypertrophy had a shorter exercise duration than those without (10.9 +/- 2.0 vs. 13.0 +/- 3.0 min, respectively; p less than 0.01). Multivariate regression analysis indicated that age, gender, systolic blood pressure, and electrocardiographic point score were all significant independent variables in predicting exercise duration (R2 = 0.48, p less than 0.0001). Exercise duration was unrelated to QRS amplitude. The authors conclude that electrocardiographic evidence of left ventricular hypertrophy, as manifested by P wave and T wave abnormalities, is associated with an impaired exercise capacity in a hypertensive population without prior myocardial infarction.
R C Bahler; K Gatzoylis
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  23     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-03-23     Completed Date:  1990-03-23     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  41-8     Citation Subset:  IM    
Division of Cardiology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
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MeSH Terms
Age Factors
Cardiomegaly / diagnosis*,  physiopathology
Heart Ventricles
Hypertension / diagnosis,  physiopathology*
Middle Aged
Prospective Studies
Retrospective Studies
Sex Factors
Grant Support

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