Document Detail

Exercise might bias skeletal-muscle fat fraction calculation from Dixon images.
MedLine Citation:
PMID:  22980761     Owner:  NLM     Status:  In-Data-Review    
We examined the influence of a single exercise session on quantitative muscle fat fraction MRI measurements. Ten healthy volunteers were scanned on a 3T body scanner before and after a session of bilateral squats until muscular fatigue. Axial in- and opposed phase images were acquired at a fixed distance from the knee joint and fat fractions were calculated using a 2-point Dixon technique as well as muscle cross sectional area at the same position. After the squat session, calculated fat fraction in the quadriceps bilaterally appeared to be significantly decreased, while all but one non-exercised muscles showed no change. In conclusion exercise might modify the measured apparent fat fraction. Trials using quantitative MRI should consider the timing of scanning sessions and physical examinations to avoid bias caused by the influence of exercise on measurements.
Arne Fischmann; Selina Kaspar; Julia Reinhardt; Monika Gloor; Christoph Stippich; Dirk Fischer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuromuscular disorders : NMD     Volume:  22 Suppl 2     ISSN:  1873-2364     ISO Abbreviation:  Neuromuscul. Disord.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111470     Medline TA:  Neuromuscul Disord     Country:  England    
Other Details:
Languages:  eng     Pagination:  S107-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
University of Basel Hospital, Department of Radiology and Nuclear Medicine, Division of Diagnostic and Interventional Neuroradiology, Petersgraben 4, CH-4031 Basel, Switzerland; University of Basel Children's Hospital, Spitalstrasse 33, CH-4056 Basel, Switzerland. Electronic address:
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