Document Detail

Exercise may cause myocardial ischemia at the anaerobic threshold in cardiac rehabilitation programs.
MedLine Citation:
PMID:  19287906     Owner:  NLM     Status:  MEDLINE    
Myocardial ischemia may occur during an exercise session in cardiac rehabilitation programs. However, it has not been established whether it is elicited when exercise prescription is based on heart rate corresponding to the anaerobic threshold as measured by cardiopulmonary exercise testing. Our objective was to determine the incidence of myocardial ischemia in cardiac rehabilitation programs according to myocardial perfusion SPECT in exercise programs based on the anaerobic threshold. Thirty-nine patients (35 men and 4 women) diagnosed with coronary artery disease by coronary angiography and stress technetium-99m-sestamibi gated SPECT associated with a baseline cardiopulmonary exercise test were assessed. Ages ranged from 45 to 75 years. A second cardiopulmonary exercise test determined training intensity at the anaerobic threshold. Repeat gated-SPECT was obtained after a third cardiopulmonary exercise test at the prescribed workload and heart rate. Myocardial perfusion images were analyzed using a score system of 6.4 at rest, 13.9 at peak stress, and 10.7 during the prescribed exercise (P < 0.05). The presence of myocardial ischemia during exercise was defined as a difference > or = 2 between the summed stress score and summed rest score. Accordingly, 25 (64%) patients were classified as ischemic and 14 (36%) as nonischemic. MIBI-SPECT showed myocardial ischemia during exercise within the anaerobic threshold. The 64% prevalence of ischemia observed in the study should not be looked on as representative of the whole population of patients undergoing exercise programs. Changes in patient care and exercise programs were implemented as a result of our finding of ischemia during the prescribed exercise.
A R C N Fuchs; R S Meneghelo; E Stefanini; A V De Paola; P E P Smanio; L E Mastrocolla; A S Ferraz; S Buglia; L S Piegas; A A C Carvalho
Related Documents :
11266196 - Continuous observation of superoxide generation in an in-situ ischemia-reperfusion rat ...
12160946 - The importance of manganese superoxide dismutase in delayed preconditioning: involvemen...
12011796 - Effects of melatonin on noncardiogenic pulmonary edema secondary to adnexial ischemia-r...
17280486 - Characterization of in vivo tissue redox status, oxygenation, and formation of reactive...
1469286 - Collagenase in wound healing: effect of wound age and type.
22506246 - The effect of power-walking in phase 2 cardiac rehabilitation program.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]     Volume:  42     ISSN:  1414-431X     ISO Abbreviation:  Braz. J. Med. Biol. Res.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8112917     Medline TA:  Braz J Med Biol Res     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  272-8     Citation Subset:  IM    
Serviço de Reabilitação Cardiovascular, Instituto Dante Pazzanese de Cardiologia, São Paulo, SP, Brasil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anaerobic Threshold / physiology*
Coronary Angiography
Coronary Artery Disease / rehabilitation
Exercise Test / adverse effects*
Heart Rate / physiology*
Middle Aged
Myocardial Ischemia / etiology*,  physiopathology,  radionuclide imaging
Radiopharmaceuticals / diagnostic use
Risk Factors
Technetium Tc 99m Sestamibi / diagnostic use
Tomography, Emission-Computed, Single-Photon
Reg. No./Substance:
0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of three exercise programs on patients with chronic obstructive pulmonary disease.
Next Document:  Demographic and metabolic characteristics of individuals with progressive glucose tolerance.