Document Detail

Exercise, magnesium and immune function.
MedLine Citation:
PMID:  18705536     Owner:  NLM     Status:  MEDLINE    
Physical exercise may deplete magnesium, which together with a marginal dietary magnesium intake may impair energy metabolism, muscle function, oxygen uptake and electrolyte balance. Consequently, the ability to perform physical work may be compromised. Many aspects of immune function can be depressed temporarily by either a single bout of very severe exercise or a longer period of excessive training. Although the disturbance is usually quite transient, it can be sufficient to allow a clinical episode of infection, particularly upper respiratory tract infections. However, regular and moderate exercise has been reported to improve the ability of the immune system to protect the host from infection. Magnesium also has a strong relation with the immune system in both non specific and specific immune responses and magnesium deficit has been shown to be related to impaired cellular and humoral immune function. Magnesium deficiency leads to immunopathological changes that are related to the initiation of a sequential inflammatory response. Although in athletes magnesium deficiency has not been investigated regarding alterations in the immune system, the possibility exists that magnesium deficiency could contribute to the immunological changes observed after strenuous exercise.
Maria José Laires; Cristina Monteiro
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Magnesium research : official organ of the International Society for the Development of Research on Magnesium     Volume:  21     ISSN:  0953-1424     ISO Abbreviation:  Magnes Res     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-08-18     Completed Date:  2008-11-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8900948     Medline TA:  Magnes Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  92-6     Citation Subset:  IM    
Biochemistry Laboratory, Faculdade de Motricidade Humana, Universidade Técnica de Lisboa, Portugal.
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MeSH Terms
Exercise / physiology*
Immune System / metabolism*
Magnesium / metabolism*
Magnesium Deficiency / immunology,  physiopathology
Physical Exertion / physiology
Reg. No./Substance:

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