Document Detail


Exercise intolerance in congestive heart failure: a lesson in exercise physiology.
MedLine Citation:
PMID:  9271764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The current working hypothesis of exercise intolerance in patients with CHF indicates that an initial reduction in cardiac output, secondary to either systolic or diastolic dysfunction, results in a variety of complex and inter-related pathophysiologic alterations in the skeletal muscle, the vasculature, the pulmonary system, and several neurohumoral systems. These numerous compensatory mechanisms, although they work to preserve vital body functions, they ultimately result in exercise intolerance. Thus, the syndrome of CHF provides a unique opportunity to evaluate the role of several fundamental principles of exercise physiology.
Authors:
P H Brubaker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of cardiopulmonary rehabilitation     Volume:  17     ISSN:  0883-9212     ISO Abbreviation:  J Cardiopulm Rehabil     Publication Date:    1997 Jul-Aug
Date Detail:
Created Date:  1997-10-02     Completed Date:  1997-10-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8511296     Medline TA:  J Cardiopulm Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  217-21     Citation Subset:  IM    
Affiliation:
Department of Medicine, Wake Forest University, Winston-Salem, North Carolina 27109, USA.
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MeSH Terms
Descriptor/Qualifier:
Exercise Test
Exercise Tolerance / physiology*
Heart Failure / physiopathology*,  rehabilitation
Hemodynamics
Homeostasis
Humans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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