Document Detail


Exercise intensity modulation of hepatic lipid metabolism.
MedLine Citation:
PMID:  22545209     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Lipid metabolism in the liver is complex and involves the synthesis and secretion of very low density lipoproteins (VLDL), ketone bodies, and high rates of fatty acid oxidation, synthesis, and esterification. Exercise training induces several changes in lipid metabolism in the liver and affects VLDL secretion and fatty acid oxidation. These alterations are even more conspicuous in disease, as in obesity, and cancer cachexia. Our understanding of the mechanisms leading to metabolic adaptations in the liver as induced by exercise training has advanced considerably in the recent years, but much remains to be addressed. More recently, the adoption of high intensity exercise training has been put forward as a means of modulating hepatic metabolism. The purpose of the present paper is to summarise and discuss the merit of such new knowledge.
Authors:
Fábio S Lira; Luiz C Carnevali; Nelo E Zanchi; Ronaldo Vt Santos; Jean Marc Lavoie; Marília Seelaender
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Publication Detail:
Type:  Journal Article     Date:  2012-04-02
Journal Detail:
Title:  Journal of nutrition and metabolism     Volume:  2012     ISSN:  2090-0732     ISO Abbreviation:  J Nutr Metab     Publication Date:  2012  
Date Detail:
Created Date:  2012-04-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526296     Medline TA:  J Nutr Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  809576     Citation Subset:  -    
Affiliation:
Laboratory of Exercise Biochemistry and Physiology, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC, Brazil.
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