| Exercise induces a change in plasma fibrinogen concentration: fact or fiction? | |
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MedLine Citation:
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PMID: 10632470 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the effect of exercise on plasma fibrinogen concentrations with simultaneous measurements of plasma volume changes. Eight moderately active males aged 26.6+/-3.6 years (mean +/- SD) completed maximal (VO2max) and submaximal (75% VO2max for 30 minutes) exercise trials separated by 7 days. Venous blood samples were obtained at rest, immediately postexercise, and following 30 minutes of recovery. Whole blood was analysed for haematocrit and haemoglobin, while citrated plasma was assayed for fibrinogen levels. Values of haematocrit and haemoglobin before and after exercise were utilised for the estimation of plasma volume changes. Plasma volume decreased (p<0.05) immediately following both maximal (-17.7+/-5.1%) and submaximal (-14.3+/-4.1%) exercise. Exercise resulted in decreased plasma fibrinogen levels (maximal exercise: from 266.3+/-14.5 to 222.2+/-23.9 mg x dL(-1); submaximal exercise: from 239.5+/-45.4 to 209.7+/-42.4 mg x dL(-1)) only when postexercise raw data were corrected for the contraction of plasma volume. It is concluded therefore that changes in plasma volume in response to exercise should be taken into account when interpreting exercise effects on plasma fibrinogen concentration. |
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Authors:
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M S El-Sayed; P G Jones; C Sale |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Thrombosis research Volume: 96 ISSN: 0049-3848 ISO Abbreviation: Thromb. Res. Publication Date: 1999 Dec |
Date Detail:
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Created Date: 2000-01-27 Completed Date: 2000-01-27 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0326377 Medline TA: Thromb Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 467-72 Citation Subset: IM |
Affiliation:
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Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, England. M.S.ElSAYED@livjm.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Exercise / physiology* Fibrinogen / metabolism* Humans Male Physical Exertion / physiology* Plasma Volume / physiology* Reference Values Time Factors |
| Chemical | |
Reg. No./Substance:
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9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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