Document Detail


Exercise-induced oxidative stress in elderly subjects: the effect of red orange supplementation on the biochemical and cellular response to a single bout of intense physical activity.
MedLine Citation:
PMID:  23297807     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Aging is characterized by an impaired capacity to maintain the redox balance both in physiological and pathological situations associated with an increased production of reactive oxygen species. Since the extent of this phenomenon may be influenced by an antioxidants rich diet, we investigated the effect of supplementation with fresh red orange juice (ROJ) on biochemical and cellular biomarkers of oxidative stress in healthy, trained elderly women after a single bout of exhaustive exercise (EE). To this purpose a sample of 22 females, 15 (69.0±5.1 years) taking the ROJ supplementation, and 7 (68.1±2.7 years) as Control group was constituted. Blood samples were collected immediately before, 30', and 24hr after a single bout of EE, at baseline and after 4 weeks. Our results demonstrate that markers of DNA damage or apoptosis were not affected by EE both in Control and ROJ group, and by ROJ, whereas exercise temporary affected the redox balance in both groups. Controls didn't change their response to EE after the experimental period, but experimental group after ROJ supplementation had lower EE-induced MDA, consumed less ascorbic acid, and had less activation of the hypoxanthine/xanthine system, i.e. they seemed to be protected from hypoxia/reoxygenation mechanisms.
Authors:
Monica Pittaluga; Antonio Sgadari; Barbara Tavazzi; Cristina Fantini; Stefania Sabatini; Roberta Ceci; Angela Maria Amorini; Paolo Parisi; Daniela Caporossi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-9
Journal Detail:
Title:  Free radical research     Volume:  -     ISSN:  1029-2470     ISO Abbreviation:  Free Radic. Res.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423872     Medline TA:  Free Radic Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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