Document Detail


Exercise-induced changes in functional residual capacity.
MedLine Citation:
PMID:  3685654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We used a helium-rebreathe technique in nine healthy subjects to determine the effects of exercise intensity and duration on end-expiratory lung volume (EELV). The rebreathe functional residual capacity (FRC) technique was shown: (a) to be similar to that measured in the body plethysmograph, at rest; (b) to agree closely with volitionally induced changes in EELV as determined by inductance plethysmography, at rest; (c) to be reproducible within subjects between trials conducted at rest or exercise on different days (r = 0.96, coefficient of variation +/- 3%); (d) to correlate significantly with coincident changes in end-expiratory esophageal pressure from rest to exercise, with increasing exercise intensity and over time at a constant exercise load. Exercise-induced reductions in EELV occurred in all subjects, averaging 0.3 L (-0.1 to -0.7 L) in light exercise and 0.79 L (-0.5 to -1.2 L) in heavy or maximum exercise. This reduction in EELV accounted for slightly more than one-half of the increase in VT during light exercise and slightly less than one-half of the increased VT in heavy exercise. In heavy prolonged exercise lasting 8-15 min, EELV fell in the initial 2 min and was either sustained at this reduced level or fell further with exercise duration to exhaustion. We found that FRC was reduced even in very light exercise when changes in TE and VE from rest were minimal; further reductions in EELV occurred as end-inspiratory lung volume increased and expiratory time shortened with increasing exercise intensity and duration. Based on these types of changes we speculate that active expiration during exercise in humans may be controlled by a combination of locomotor-related feed-forward and lung volume related feed-back mechanisms.
Authors:
M T Sharratt; K G Henke; E A Aaron; D F Pegelow; J A Dempsey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration physiology     Volume:  70     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-14     Completed Date:  1988-01-14     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  313-26     Citation Subset:  IM; S    
Affiliation:
John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Madison 53705.
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MeSH Terms
Descriptor/Qualifier:
Adult
Breath Tests
Esophagus / physiology
Female
Functional Residual Capacity*
Helium
Humans
Lung Volume Measurements*
Male
Middle Aged
Physical Exertion
Respiration
Chemical
Reg. No./Substance:
7440-59-7/Helium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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