Document Detail

Exercise-induced cardiac injury: evidence from novel imaging techniques and highly sensitive cardiac troponin assays.
MedLine Citation:
PMID:  22386291     Owner:  NLM     Status:  MEDLINE    
Prolonged endurance exercise in humans has been associated with an acute impairment in diastolic and systolic cardiac function and the release of cardiac troponin. In this chapter, we review recent evidence from studies using novel echocardiographic parameters and highly sensitive cardiac troponin assays. We demonstrate that the mechanics of left and right ventricular functions are acutely impaired after completion of prolonged exercise and that this reduction in function is likely multifactorial in etiology. However, we highlight that exercise-induced cardiac troponin release is not a marker of exercise-induced pathology but likely a physiologic response to exercise. Finally, we discuss the potential link between prolonged exercise and the increased incidence of cardiac pathology in veteran athletes.
Rob Shave; David Oxborough
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  54     ISSN:  1873-1740     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    2012 Mar-Apr
Date Detail:
Created Date:  2012-03-05     Completed Date:  2012-04-23     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  407-15     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Cardiff School of Sport, Cardiff Metropolitan University, Cyncoed Campus, Cardiff, UK.
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MeSH Terms
Adaptation, Physiological
Biological Markers / blood
Diagnostic Imaging* / methods
Physical Endurance
Predictive Value of Tests
Troponin / blood*
Ventricular Dysfunction, Left / blood,  diagnosis*,  etiology,  physiopathology
Ventricular Dysfunction, Right / blood,  diagnosis*,  etiology,  physiopathology
Ventricular Function, Left
Ventricular Function, Right
Reg. No./Substance:
0/Biological Markers; 0/Troponin

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