Document Detail

Exercise-induced biochemical modifications in muscle in chronic kidney disease: occult acidosis as a potential factor limiting the anabolic effect of exercise.
MedLine Citation:
PMID:  21195921     Owner:  NLM     Status:  In-Process    
There is growing evidence that exercise may be beneficial in limiting or reversing problems related to chronic kidney disease (CKD); but exercise therapy has had limited success in increasing lean body mass, implying that metabolic abnormalities in muscle during CKD may limit the anabolic effectiveness of exercise. This short review summarizes evidence that exercise may result in a transient worsening of the pre-existing metabolic acidosis that occurs in these patients; a metabolic defect that may reverse the normal anabolic effects of exercise.
Emma L Clapp; Alan Bevington
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation     Volume:  21     ISSN:  1532-8503     ISO Abbreviation:  J Ren Nutr     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112938     Medline TA:  J Ren Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  57-60     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, United Kingdom.
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